Autopsy report for a caffeine intoxication case and review of the current literature

作者：Yamamoto Takuma^*; Yoshizawa Katsuhiko; Kubo Shin ichi; Emoto Yuko; Hara Kenji; Watcrs Brian; Umehara Takahiro; Murase Takehiko; Ikematsu Kazuya

来源：Journal of Toxicologic Pathology, 2015, 28(1): 32-35.

DOI：10.1293/tox.28.2014-0044

• caffeine
• intoxication
• autopsy
• pathology
• suicide

Caffeine (1,3,7-trimethylxanthine) is a popular mild central nervous system stimulant found in the leaves, seeds and fruits of various plants and in foodstuffs such as coffee, tea, and chocolate, among others. Caffeine is widely used and is not associated with severe side effects when consumed at relatively low doses. Although rarely observed, overdoses can occur. However, only a few fatal caffeine intoxication cases have been reported in the literature. Herein, we report the pathological examination results and information on caffeine concentrations in the blood, urine and main organs in a fatal caffeine intoxication case. Even though high caffeine concentrations were found in the systemic organs, no caffeine-related pathological changes were detected.

• 出版日期2015-1