A Tandem Aldol-Diels-Alder Reaction Accelerated in Water: An Approach to the Catalyst-Free One-Pot Synthesis of Spiro Thio-Oxindoles

作者：Moghaddam F Matloubi^*; Hojabri L; Taheri S; Pirani P

来源：Journal of the Iranian Chemical Society, 2010, 7(3): 781-790.

• Spiro thio-oxindoles
• Aldol-Diels-Alder reaction
• Dimerization
• alpha,beta-Unsaturated thio-oxindole

Spiro thio-oxindoles are prepared in situ by the reaction of the corresponding aldehydes and thio-oxindoles in a straightforward, environmentally friendly, highly efficient and simple procedure. The reaction took place in water with no catalyst added. This one-pot reaction afforded regio- and diastereoselective products in high yields (61-93%).

• 出版日期2010-9