Determination of 38 Kinds of Pesticide Residues in Nuts by QuEChERS-Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry

作者：Dong Ya-Lei; Liu Wen-Jing; Cao Jin^*; Wang Gang-Li

来源：Chinese Journal of Analytical Chemistry, 2017, 45(9): 1397-1404.

DOI：10.11895/j.issn.0253.3820.160885

• Ultra-high performance liquid chromatography-tandem mass spectrometry
• QuEChERS
• Multi-pesticide residues
• Nuts

A multi-residue analysis method was developed for the determination of 38 kinds of pesticides in nuts (almonds, peanuts, cashew nuts and walnuts) by QuEChERS-ultra-high performance liquid chromatography-tandem mass spectrometry. The pesticide residues were extracted with acetonitrile. The extract was cleaned up with PSA, C-18 and Oasis PRiME HLB, and then analyzed by UPLC-MS/MS with multiple reaction monitoring (MRM) mode. External standard method was employed to quantify. The limits of detection (LODs, S/N = 3) of this method were between 0.01 and 10 mu g/kg, and the limits of quantitation (LOQs, S/N = 10) were between 0.05-20 mu g/kg. All of the tested pesticides showed good linear relationship (r>0. 991). The practical samples were determined at three spiked levels and the average recoveries were between 51.0% and 126.0%. The RSDs were less than 20%. This method was simple, sensitive and accurate, and could be used for the routine analysis of pesticide residues in nuts.

• 出版日期2017-9
• 单位中国药科大学