Modular approach for bimodal antibacterial surfaces combining photo-switchable activity and sustained biocidal release

作者：Pallavicini Piersandro^*; Bassi Barbara; Chirico Giuseppe; Collini Maddalena; Dacarro Giacomo; Fratini Emiliano; Grisoli Pietro; Patrini Maddalena; Sironi Laura; Taglietti Angelo^*; Moritz Marcel; Sorzabal Bellido Ioritz; Susarrey Arce Arturo; Latter Edward; Beckett Alison J; Prior Ian A; Raval Rasmita^*; Fernandez Yuri A Diaz^*

来源：Scientific Reports, 2017, 7(1): 5259.

DOI：10.1038/s41598-017-05693-3

Photo-responsive antibacterial surfaces combining both on-demand photo-switchable activity and sustained biocidal release were prepared using sequential chemical grafting of nano-objects with different geometries and functions. The multi-layered coating developed incorporates a monolayer of near-infrared active silica-coated gold nanostars (GNS) decorated by silver nanoparticles (AgNP). This modular approach also enables us to unravel static and photo-activated contributions to the overall antibacterial performance of the surfaces, demonstrating a remarkable synergy between these two mechanisms. Complementary microbiological and imaging evaluations on both planktonic and surface-attached bacteria provided new insights on these distinct but cooperative effects.

• 出版日期2017-7-12