Donor transmission of malignant melanoma in a lung transplant recipient 32 years after curative resection

作者：Bajaj Navkaranbir S; Watt Christopher; Hadjiliadis Denis; Gillespie Colin; Haas Andrew R; Pochettino Alberto; Mendez James; Sterman Daniel H; Schuchter Lynn M; Christie Jason D; Lee James C; Ahya Vivek N^*

来源：Transplant International, 2010, 23(7): e26-e31.

DOI：10.1111/j.1432-2277.2010.01090.x

• donor selection criteria
• long-term complications
• lung transplantation (clinical)
• malignancies
• organ donation

P>In the current era of organ shortages and long wait times for life-saving transplants, marginal or extended donors are increasingly being considered; one such category of marginal organs is from donors with a previous history of malignancy. Melanoma in particular has been associated with increased risk of developing late recurrence. In this report, we describe a case of fatal donor melanoma transmission to a 64-year-old lung transplant recipient 32 years after surgical excision of the melanoma. Based on this report and review of the available literature, we conclude that a history of donor melanoma, regardless of the stage and time interval from 'curative' surgical resection, should remain a strong relative contraindication to transplantation.

• 出版日期2010-7