Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer

作者:Schiavon Gaia; Hrebien Sarah; Garcia Murillas Isaac; Cutts Rosalind J; Pearson Alex; Tarazona Noelia; Fenwick Kerry; Kozarewa Iwanka; Lopez Knowles Elena; Ribas Ricardo; Nerurkar Ashutosh; Osin Peter; Chandarlapaty Sarat; Martin Lesley Ann; Dowsett Mitch; Smith Ian E; Turner Nicholas C
来源:Science Translational Medicine, 2015, 7(313): 313ra182.
DOI:10.1126/scitranslmed.aac7551

摘要

<jats:p> <jats:italic>ESR1</jats:italic> mutations evolve during the treatment of metastatic breast cancer. </jats:p>

  • 出版日期2015-11-11