A copper-based catalytic system for carboxylation of terminal alkynes: synthesis of alkyl 2-alkynoates

作者:Inamoto Kiyofumi*; Asano Narumi; Kobayashi Koji; Yonemoto Misato; Kondo Yoshinori
来源:Organic and Biomolecular Chemistry, 2012, 10(8): 1514-1516.
DOI:10.1039/c2ob06884b

摘要

An efficient coupling of terminal alkynes and CO2 in the presence of alkyl halides can be achieved under ambient conditions using a copper/phosphine catalyst system, providing facile access to a variety of functionalised alkyl 2-alkynoates.

  • 出版日期2012