An efficient method for the synthesis of substituted 5-aminotetrazoles from selenoureas using PhI(OAc)2

作者：Xie, Yuanyuan^*; Guo, Dongyan; Jiang, Xiaoying; Pan, Haixuan; Wang, Wenhui; Jin, Tingting; Mi, Zhisheng

来源：Tetrahedron Letters, 2015, 56(19): 2533-2536.

DOI：10.1016/j.tetlet.2015.03.128

• Selenourea
• Sodium azide
• Diacetoxyiodobenzene
• 5-Aminotetrazoles
• Electrocyclization

An efficient method to access 5-aminotetrazoles starting from readily accessible 1,3-disubtituted selenoureas has been discovered. This is the first example of the synthesis of 5-aminotetrazoles involving the use of diacetoxyiodobenzene (DIB). The reaction is in line with the requirements of green chemistry by virtue of mild conditions, environmental benign, short reaction time, and good selectivity.

• 出版日期2015-5-6
• 单位浙江工业大学