Necrotizing soft tissue infection caused by Serratia marcescens: A case report and literature review

作者：Hagiya Hideharu^*; Ojima Masahiro; Yoshida Takeshi; Matsui Takahiro; Morii Eiichi; Sato Kazuaki; Tahara Shinichiro; Yoshida Hisao; Tomono Kazunori

来源：Journal of Infection and Chemotherapy, 2016, 22(5): 335-338.

DOI：10.1016/j.jiac.2015.11.013

• Necrotizing soft tissue infection
• Necrotizing fasciitis
• Serratia marcescens
• Sepsis

A 64-year-old man with advanced liver cirrhosis was transferred to an emergency center due to septic shock and markedly inflamed left leg. Under a clinical diagnosis of necrotizing soft tissue infection (NSTI), the patient undertook intensive therapy but died 25 h after arrival. The pathogenic organism, Serratia marcescens, was later isolated from blood and soft tissue cultures. NSTI is very rarely associated with S. marcescens. A literature review showed that only 16 such cases, including our case, have been reported to date. Our case is the first evidence of an S. marcescens NSTI in a patient with liver cirrhosis. S. marcescens NSTI has an extremely high mortality rate; total mortality and mortality in cases involving the extremities were 75% (12 of 16 cases) and 83.3% (10 of 12 cases), respectively. Physicians need to be aware that S. marcescens can induce fatal infections in community patients.

• 出版日期2016-5