Detection of a Possible Bioterrorism Agent, Francisella sp., in a Clinical Specimen by Use of Next-Generation Direct DNA Sequencing

作者：Kuroda Makoto^*; Sekizuka Tsuyoshi; Shinya Fumiaki; Takeuchi Fumihiko; Kanno Takayuki; Sata Tetsutaro; Asano Shigeyuki

来源：Journal of Clinical Microbiology, 2012, 50(5): 1810-1812.

DOI：10.1128/JCM.06715-11

Deep sequencing detected a potential bioterrorism agent, Francisella tularensis, in a human abscess sample (Iwaki-08) of un-known etiology. Identified single-nucleotide variations suggest that the Iwaki-08 case was associated with Francisella tularensis subsp. holarctica (biovar japonica) but not the highly virulent type A (Francisella tularensis subsp. tularensis).

• 出版日期2012-5