Disulfides as efficient thiolating reagents enabling selective bis-sulfenylation of aryl dihalides under mild copper-catalyzed conditions

作者：Liu, Yunyun^*; Wang, Hang; Zhang, Jida; Wan, Jie-Ping; Wen, Chengping

来源：RSC Advances, 2014, 4(37): 19472-19475.

DOI：10.1039/c4ra02935f

• C-S
• COUPLING REACTIONS
• BOND FORMATION
• ROOM-TEMPERATURE
• BORONIC ACIDS
• THIOLS
• IODIDES
• HALIDES
• ARYLATION
• LIGAND

Selective bis-sulfenylation reactions of aryl dihalides have been achieved by copper-catalyzed C-S coupling reactions under mild conditions of refluxing EtOH (80 degrees C). Employment of disulfides as thiolating reagents enables the production of various bis(phenylthio) benzenes with excellent selectivity, and no products from mono C-S coupling are isolated.

• 出版日期2014
• 单位江西师范大学; 浙江中医药大学