Ammonium metavanadate: an effective catalyst for synthesis of alpha-hydroxyphosphonates

作者：Sonar Swapnil S; Kategaonkar Amol H; Ware Madhav N; Gill Charansingh H; Shingate Bapurao B; Shingare Murlidhar S^*

来源：Arkivoc, 2009, 2009(2): 138-148.

DOI：10.3998/ark.5550190.0010.215

• Ammonium metavanadate (NH(4)VO(3))
• alpha-hydroxyphosphonate
• aldehyde
• triethyl phosphite
• solvent-free

Ammonium metavanadate (NH(4)VO(3)) is an inexpensive, efficient and mild catalyst for the synthesis of alpha-hydroxyphosphonate derivatives by the reaction of various aryl or heteroaryl aldehydes with triethylphosphite at room temperature. This method affords the alpha-hydroxyphosphonates in short reaction times, under solvent-free conditions, and in high yield.

• 出版日期2009