A Green Synthesis of Pyrido[1,2-a]quinazoline-1,6-dione Derivatives in Ionic Liquid Catalyzed by Iodine

作者:Lu Lian; Zhang Mei Mei; Wang Xiang Shan*
来源:Journal of Heterocyclic Chemistry, 2014, 51(S1): E314-E317.
DOI:10.1002/jhet.1837

摘要

A mild, green, and facile route to the synthesis of 3,4,4a,5-tetrahydro-4a-methyl-2H-pyrido[1,2-a]quinazoline-1,6-dione derivatives has been developed. In the presence of iodine, a variety of 2-aminobenzamides underwent a tandem reaction with 6-chlorohexan-2-one to afford the corresponding pyridoquinazolines in good to high yields.

  • 出版日期2014-8