A B-1-Insensitive High Resolution 2D T-1 Mapping Pulse Sequence for dGEMRIC of the HIP at 3 Tesla

作者：Lattanzi Riccardo^*; Glaser Christian; Mikheev Artem V; Petchprapa Catherine; Mossa David J; Gyftopoulos Soterios; Rusinek Henry; Recht Michael; Kim Daniel

来源：Magnetic Resonance in Medicine, 2011, 66(2): 348-355.

DOI：10.1002/mrm.23035

• femoroacetabular impingement
• MRI
• hip
• cartilage
• dGEMRIC
• radial MRI
• T-1 mapping
• B1+ inhomogeneity

Early detection of cartilage degeneration in the hip may help prevent onset and progression of osteoarthritis in young patients with femoroacetabular impingement. Delayed gadolinium-enhanced MRI of cartilage is sensitive to cartilage glycosaminoglycan loss and could serve as a diagnostic tool for early cartilage degeneration. We propose a new high resolution 2D T-1 mapping saturation-recovery pulse sequence with fast spin echo readout for delayed gadolinium-enhanced magnetic resonance imaging of cartilage of the hip at 3 T. The proposed sequence was validated in a phantom and in 10 hips, using radial imaging planes, against a rigorous multipoint saturation-recovery pulse sequence with fast spin echo readout. T-1 measurements by the two pulse sequences were strongly correlated (R-2 > 0.95) and in excellent agreement (mean difference = -8.7 ms; upper and lower 95% limits of agreement = 64.5 and -81.9 ms, respectively). T-1 measurements were insensitive to B1+ variation as large as 20%, making the proposed T-1 mapping technique suitable for 3 T. Magn Reson Med 66:348-355,2011.

• 出版日期2011-8