Development of a new computerized prism adaptation procedure for visuo-spatial neglect

作者：Champod Anne Sophie^*; Taylor Kristina; Eskes Gail A

来源：Journal of Neuroscience Methods, 2014, 235: 65-75.

DOI：10.1016/j.jneumeth.2014.05.023

• Prism adaptation
• After-effects
• Visuo-spatial neglect
• Rehabilitation

Background: Prism adaptation (PA) is a promising rehabilitation technique for visuo-spatial neglect. However, PA effects are often inconsistent across studies and the clinical application of this technique has been limited. The purpose of the present studies was to validate an easily standardized, home-friendly, and game-like PA technique (Peg-the-Mole) with healthy participants as a first step toward clinical development. %26lt;br%26gt;New method: In study 1, we used Peg-the-Mole with 32 participants wearing prism or sham goggles to investigate whether this procedure can induce significant after-effects on midline judgment and pointing tasks. In study 2, we compared Peg-the-Mole to a typical PA protocol in 42 participants for after-effects and level of enjoyment and to determine if the after-effects generalize to a throwing task. %26lt;br%26gt;Results and comparison with existing method: Study 1 showed that Peg-the-Mole induced significant aftereffects on all outcome measures. Study 2 demonstrated that after-effects induced by Peg-the-Mole were equivalent to those induced by the typical PA procedure on all outcome measures. Peg-the-Mole was rated as more enjoyable than the typical procedure. %26lt;br%26gt;Conclusions: Peg-the-Mole is a new computerized PA procedure that can be easily standardized and successfully used to induce significant after-effects. The present findings demonstrate that alterations can be made to the typical PA procedure to make it easier to use and more enjoyable, factors that could increase treatment availability, adherence and intensity.

• 出版日期2014-9-30