Mechanism of autograft insufficiency after the Ross operation in children

作者：Goda Motohiko^*; Gewillig Marc; Eyskens Benedicte; Heying Ruth; Cools Bjorn; Rega Filip; Meyns Bart

来源：Cardiology in the Young, 2013, 23(4): 523-529.

DOI：10.1017/S1047951112001783

• Congenital valve disease
• aortic valve
• pulmonary valve
• child
• Z score
• Kaplan-Meier method

Background: It is unclear how autografts grow and dilate after the Ross operation in children. We analysed autograft growth and dilatation in children who underwent the Ross operation and examined the relationship of these factors to autograft failure. Methods: From our institutional database, we retrospectively identified 33 children who underwent the Ross operation without aortic root reinforcement (mean age 9.9 years) and had normal body measurements and echocardiographic data throughout follow-up. Results: Autograft insufficiency developed in 10 patients 5.1 years after the Ross operation. The average Z score at the development of autograft insufficiency was -0.1 (range from -2.0 to 6.1). The proportions of patients who remained free of autograft insufficiency at 5 and 10 years were 87.2% and 55.7%, respectively. A consistent trend in the time course of Z score was not found in any age group studied. Conclusions: Autograft growth and dilation after the Ross operation varied widely among patients, and the incidence of autograft insufficiency was independent of annulus size.

• 出版日期2013-8