Ammonium carbamate; mild, selective and efficient ammonia source for preparation of beta-amino-alpha,beta-unsaturated esters at room temperature

作者：Litvic M^*; Filipan M; Pogorelic I; Cepanec I

来源：Green Chemistry, 2005, 7(11): 771-774.

DOI：10.1039/b510276f

Ammonium carbamate can be used as a very effective reagent for preparation of different substituted beta-amino-alpha,beta-unsaturated esters in methanol at room temperature. The product is isolated without aqueous work-up in high purity and excellent yield. The method is simple and easily scaled-up.

• 出版日期2005