A simple pyrazoline-based fluorescent probe for Zn2+ in aqueous solution and imaging in living neuron cells

作者:Zhang Ting Ting; Wang Fang Wu; Li Meng Meng; Liu Jin Ting; Miao Jun Ying; Zhao Bao Xiang*
来源:Sensors and Actuators B: Chemical , 2013, 186: 755-760.
DOI:10.1016/j.snb.2013.06.085

摘要

A simple pyrazoline-based highly sensitive fluorescent probe for Zn2+ in aqueous solution and biological Zn2+ detection has been developed. The probe displays a good selective fluorescence enhancement (13-fold) for Zn2+ over various metal ions. The new probe is cell-permeable and can be successfully used to image intracellular Zn2+ in living neuron cells.