科研之友
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摘要
Damaging effects of photoexcited TiO2 nanoparticles on gastric cancer SGC-7901 cells were investigated. The influences of nanosized TiO2 content, and irradiation time on cancer inhibition were systematically studied, and the inhibition mechanism was primarily discussed. The results demonstrate that photoexcited TiO2 nanoparticles exhibit good inhibition effects on gastric cancer SGC-7901 cells, and this process follows approximately first-order reaction rule. While the concentration of TiO2 nanoparticles is about 300 mu g/mL, the damaging effects are rather remarkable. In addition, the exhibition forms of gastric cancer SGC-7901 cells are apoptosis and necrosis in killing experiments. Taken together, damaging effects of photoexcited TiO2 nanoparticles on gastric cancer SGC-7901 cells might be attributed to the reactive oxygen species formed on the TiO2 nanoparticles surface.
