Near-infrared absorbing and luminescent gold speckled silica nanoparticles for photothermal therapy

作者:Sharma Parvesh; Brown Scott C; Singh Amit; Iwakuma Nobutaka; Pyrgiotakis Georgios; Krishna Vijay; Knapik Jacquelyn A; Barr Keira; Moudgil Brij M*; Grobmyer Stephen R
来源:Journal of Materials Chemistry, 2010, 20(25): 5182-5185.
DOI:10.1039/c0jm00354a

摘要

Herein, we report the development and functional evaluation of sub-50 nm near-infrared absorbing and luminescent gold speckled silica (GSS) nanoparticles for fluorescence traceable and selective, in vitro and in vivo photothermal ablation applications. The nanoparticles prepared using microemulsion-mediated approach, are comprised of GRAS (generally regarded as safe) materials, and are promising multifunctional agents for image guided photo-mediated therapies.

  • 出版日期2010