An efficient one-pot oxidative esterification of aldehydes to carboxylic esters using B(C6F5)(3)-TBHP

作者：Guggilapu Sravanthi Devi; Prajapti Santosh Kumar; Babu Bathini Nagendra^*

来源：Tetrahedron Letters, 2015, 56(7): 889-892.

DOI：10.1016/j.tetlet.2015.01.033

• Aldehyde
• Oxidative esterification
• Tris(pentafluorophenyl)borane
• tert-Butyl hydroperoxide

A simple and efficient protocol for oxidative esterification of diverse aldehydes with alcohols was accomplished with tert-butyl hydroperoxide and 1 mol % of tris(pentafluorophenyl)borane [B(C6F5)(3)] to generate the corresponding esters in good to excellent yields. The present protocol represents compatibility with wide range of functional groups as well as exceptional tolerance toward acid labile protecting groups such as TBDPS, TBDMS, acetonide, and Boc.

• 出版日期2015-2-11