Musculoskeletal Deterioration in Men Accompanies Increases in Body Fat

作者：Pasco Julie A^*; Gould Haslinda; Brennan Sharon L; Nicholson Geoff C; Kotowicz Mark A

来源：Obesity, 2014, 22(3): 863-867.

DOI：10.1002/oby.20496

Objective: To examine body fat and musculoskeletal changes in men over 5 years. %26lt;br%26gt;Methods: Body composition was evaluated for men in the Geelong Osteoporosis Study using whole body dual energy X-ray absorptiometry (DXA) during two time-periods. DXA was performed for 1329 men (25-96 years) during 2001-2006 and for 900 men (25-98 years), 2006-2011. The masses of fat, lean, and bone were expressed relative to the square of height (kg= m 2). Each compartment was also expressed as a percentage relative to body weight (% fat, % lean, % bone). %26lt;br%26gt;Results: Mean BMI increased from 26.9 kg= m(2) in 2001-2006, to 27.2 kg= m(2) in 2006-2011 (P 5 0.04). Mean fat mass increased by 9.0% from 6.98 kg= m(2) (95% CI 6.84-7.11) in 2001-2006, to 7.60 kg= m(2) (7.44-7.77) in 2006-2011 (P %26lt; 0.001); mean lean mass decreased by 0.9%, from 18.92 kg= m(2) (18.8319.01) to 18.75 kg= m(2) (18.64-18.86) (P 5 0.02), and mean bone mass decreased 1.6% from 1.041 kg= m(2) (1.034-1.047), to 1.024 kg= m(2) (1.016-1.032). Mean % fat increased from 23.4% to 25.2%, mean % lean decreased from 72.6% to 70.9% and mean % bone decreased from 4.0% to 3.9% (all P %26lt; 0.05). %26lt;br%26gt;Conclusions: An increase in BMI, which reflects a substantial increase in body fat mass and declines in both lean and bone mass was reported. This may have implications for future development of bone fragility, sarcopenia, and sarcopenic obesity.

• 出版日期2014-3
• 单位迪肯大学