Neuropsychology of reward learning and negative symptoms in schizophrenia

作者：Nestor Paul G^*; Choate Victoria; Niznikiewicz Margaret; Levitt James J; Shenton Martha E; McCarley Robert W

来源：Schizophrenia Research, 2014, 159(2-3): 506-508.

DOI：10.1016/j.schres.2014.08.028

• Schizophrenia
• Reward learning
• Iowa Gambling Test
• Negative symptoms

We used the Iowa Gambling Test (IGT) to examine the relationship of reward learning to both neuropsychological functioning and symptom formation in 65 individuals with schizophrenia. Results indicated that compared to controls, participants with schizophrenia showed significantly reduced reward learning, which in turn correlated with reduced intelligence, memory and executive function, and negative symptoms. The current findings suggested that a disease-related disturbance in reward learning may underlie both cognitive and motivation deficits, as expressed by neuropsychological impairment and negative symptoms in schizophrenia.

• 出版日期2014-11