A one-pot oxidation/allylation/oxidation sequence for the preparation of beta,gamma-unsaturated ketones directly from primary alcohols

作者：Moody Catherine L; Pugh David S; Taylor Richard J K^*

来源：Tetrahedron Letters, 2011, 52(19): 2511-2514.

DOI：10.1016/j.tetlet.2011.03.033

• Oxidation
• Allylation
• beta,gamma-Unsaturated ketones
• alpha,beta-Unsaturated ketones

A one-pot oxidation/allylation/oxidation procedure has been developed for the conversion of primary alcohols into beta,gamma-unsaturated ketones. The methodology has been applied to a range of alcohols, and in some cases, isomerisation to produce the corresponding alpha,beta-unsaturated ketones has been carried out.

• 出版日期2011-5-11