Assessment of Single-Bolus Contrast Administration Technique Using Hybrid Dual-Source ECG-Gated Thoracic and Dual-Source Non-ECG-Gated High-Pitch Abdominopelvic CT Acquisitions for Procedural Planning Before Transcatheter Aortic Valve Replacement

作者：Walker Wendy L; Boll Daniel T; Bueno Juliana M; Kiefer Todd L; Vavalle John P; Gaca Jeffrey G; Harrison J Kevin; Hughes G Chad; Wang Andrew; Hurwitz Lynne M^*

来源：Journal of Computer Assisted Tomography, 2015, 39(2): 207-212.

DOI：10.1097/rct.0000000000000194

• aortic stenosis
• transcatheter aortic valve replacement
• computed tomographic angiography

Purpose: This study aimed to assess vascular contrast opacification and homogeneity using single-bolus contrast administration with hybrid thoracic and abdominopelvic computed tomographic angiography in patients with severe aortic valve stenosis.
Materials and Methods: Combination electrocardiogram-gated thoracic and dual-source, high-pitch abdominopelvic computed tomographic angiography examinations of 50 patients with severe aortic stenosis between December 2013 and March 2014 were reviewed. Contrast administration was individualized to patient-specific physiology. Image analysis of vascular opacificationwas obtained and interdependencies of vascular contrast and homogeneity of contrast distribution were assessed.
Results: The mean volume of contrast administered was 106 +/- 11.7 mL. Mean attenuation was 371 +/- 90.7 Hounsfield units (HU) in the thoracic aorta and 388 +/- 95.9 HU in the abdominal aorta. Homogeneous opacification was obtained throughout with coefficient of variation of 11%.
Conclusions: Procedural planning for transcatheter aortic valve replacement can be achieved using a single-injection bolus contrast protocol in combination with a 2-part multidetector computed tomographic image acquisition technique with optimal opacification of major arterial structures.

• 出版日期2015-4