HiGlass: web-based visual exploration and analysis of genome interaction maps

作者：Kerpedjiev Peter; Abdennur Nezar; Lekschas Fritz; McCallum Chuck; Dinkla Kasper; Strobelt Hendrik; Luber Jacob M; Ouellette Scott B; Azhir Alaleh; Kumar Nikhil; Hwang Jeewon; Lee Soohyun; Alver Burak H; Pfister Hanspeter; Mirny Leonid A; Park Peter J; Gehlenborg Nils^*

来源：Genome Biology, 2018, 19(1): 125.

DOI：10.1186/s13059-018-1486-1

• Hi-C
• Data visualization
• Chromosome conformation
• Genomics

We present HiGlass, an open source visualization tool built on web technologies that provides a rich interface for rapid, multiplex, and multiscale navigation of 2D genomic maps alongside 1D genomic tracks, allowing users to combine various data types, synchronize multiple visualization modalities, and share fully customizable views with others. We demonstrate its utility in exploring different experimental conditions, comparing the results of analyses, and creating interactive snapshots to share with collaborators and the broader public. HiGlass is accessible online at http://higlass.io and is also available as a containerized application that can be run on any platform.

• 出版日期2018-8-24
• 单位MIT