摘要
There is growing interest in the connection between neurological soft signs (NSS) and schizophrenia spectrum disorders such as schizotypal personality disorder. The association between NSS and schizotypy was investigated in a subgroup of 169 young healthy male military conscripts included in the Athens Study of Psychosis Proneness and Incidence of Schizophrenia. During their first 2 weeks in the National Basic Air Force Training Centre (T-1-first assessment), subjects completed the Schizotypal Personality Questionnaire (SPQ), the Symptom Checklist-90 Revised (SCL-90-R), and the Raven%26apos;s Progressive Matrices (RPM). Then, 2 years later (T-2-second assessment), at the time of military discharge, they were tested for NSS with the Neurological Evaluation Scale (NES) and reevaluated with the SPQ the SCL-90-R and additionally the Structured Clinical Interview for Personality Disorders (SCID-II) for the Diagnostic and Statistical Manual of Mental Disorders Third Edition, Revised (DSM-III-R). NSS were more prominent in conscripts with high schizotypy; scores on Sequencing of Complex Motor Acts (SCMA) and the %26quot;Other Soft Signs%26quot; (OSS) subscales were correlated with high schizotypy at both T-1 and T-2. Increased levels of SCMA as well as the total NSS score were correlated at both T-1 and T-2 with the interpersonal SPQ factor (reflecting negative schizotypy). The findings support the proposal that negative schizotypy might be associated with subtle neurodevelopmental abnormalities.
- 出版日期2012-7-30