A NEW SPIROTRYPROSTATIN FROM THE MARINE ISOLATE OF THE FUNGUS Aspergillus fumigatus

作者：Afiyatullov Sh Sh^*; Zhuravleva O I; Chaikina E L; Anisimov M M

来源：Chemistry of Natural Compounds, 2012, 48(1): 95-98.

DOI：10.1007/s10600-012-0166-8

• spirotryprostatin
• marine isolate of the fungus Aspergillus fumigatus
• NMR spectroscopy
• soy
• buckwheat
• corn sprout roots

The new spirocyclic diketopiperazine alkaloid spirotryprostatin F was isolated from the marine isolate of the fungus Aspergillus fumigatus. The structure of the compound was established using on NMR spectroscopy, high-resolution mass spectrometry, and acid hydrolysis. Spirotryprostatin F in low and ultralow doses (10(-6)-10(-17) M) exhibited stimulating action on the growth of sprout roots of soy [Glycine max (L.) Merr.], buckwheat (Fagopyrum esculentum Moench), and corn (Zea mays L.). The dose-effect curve had a bimodal character.

• 出版日期2012-3