A Shortcut to Activity-Dependent Transcription

作者:Sharma Nikhil; Gabel Harrison W; Greenberg Michael E*
来源:Cell, 2015, 161(7): 1496-1498.
DOI:10.1016/j.cell.2015.06.009

摘要

Neuronal activity results in the rapid induction of gene transcription through a series of defined molecular events. Madabhushi et al. describe an unexpected role for the cutting of promoter DNA by topoisomerase IIB to facilitate transcription of activity-induced genes.

  • 出版日期2015-6-18