Assessment of Left Atrial Reservoir Function in Mitral Valve Disease by Tissue Doppler, Strain and Strain Rate Imaging

作者：Ojaghi Haghighi Zahra; Mostafavi Atoosa^*; Moladoust Hassan; Noohi Feridoun; Maleki Majid; Esmaeilzadeh Maryam; Samiei Niloofar

来源：Journal of Medical Imaging and Health Informatics, 2014, 4(5): 705-711.

DOI：10.1166/jmihi.2014.1309

• Echocardiography
• Left Atrial
• Mitral Stenosis
• Mitral Regurgitation
• Strain

Introduction: Mitral valve stenosis and mitral valve regurgitation still result in significant morbidity and mortality. It has been shown that atrial remodeling and atrial fibrillation may occur in these patients. We sought to investigate how pressure or volume overload in the left atrium could impact atrial deformation properties obtained via Doppler-derived velocity and strain/strain rate imaging. Methods: Thirty-six patients, comprising 17 patients with a diagnosis of moderate to severe mitral stenosis and 19 patients with a diagnosis of moderate to severe mitral regurgitation, were compared with 16 healthy subjects. Two-dimensional, pulse Doppler, and tissue Doppler transthoracic echocardiographic study was performed. Measurement of regional velocity, strain and SR profiles, peak systolic velocity, peak strain, and strain rate was performed in two segments of the four left atrial walls. Results: There was a significant decline in peak systolic velocity in the mitral stenosis patients in both annular and roof segments, but the difference was not statistically significant between the mitral regurgitation patients and the healthy subjects. Total velocity was significantly lower in the mitral stenosis patients than in the healthy subjects, but the difference was not statistically significant between the healthy subjects and the mitral regurgitation patients. Comparison of total strain showed significant differences between the three groups mainly due to a decline in strain in the mitral stenosis patients in comparison with the other two groups. Comparison of total peak systolic strain rate between the groups showed significant differences due to a significant decline in the mitral stenosis group and a non-significant decline in the mitral regurgitation group by comparison with the healthy group. Conclusion: This reduction, especially in strain and strain rate, shows that the reservoir function of the left atrium could be compromised more severely in asymptomatic mitral stenosis patients.

• 出版日期2014-10