A novel synthesis of trifluoromethylated multi-substituted alkenes via regio- and stereoselective Heck reaction of (E)-4,4,4-trifluoro-1-phenyl-2-buten-1-one

作者：Konno Tsutomu^*; Yamada Shigeyuki; Tani Akinori; Miyabe Tomotsugu; Ishibara Takashi

来源：Synlett, 2006, (18): 3025-3028.

DOI：10.1055/s-2006-951496

• Heck reaction
• aryldiazonium salts
• fluoroorganic compounds

Treatment of (E)-4,4,4-trifluoro-1-phenyl-2-buten-1-one with various aryldiazonium salts in the presence of a palladium catalyst led to a smooth Heck reaction, furnishing alpha-arylated adducts in good yields.

• 出版日期2006-11-3