Gold-catalyzed cyclization of propargylic diynes: Ethers vs acetates - Related products but different pathways

作者:Schaedlich Johannes; Lauterbach Tobias; Rudolph Matthias; Rominger Frank; Hashmi A Stephen K*
来源:Journal of Organometallic Chemistry, 2015, 795: 71-77.
DOI:10.1016/j.jorganchem.2015.04.053

摘要

Diyne substrates bearing one propargylic ether instead of the previously published propargylic acetates were subjected to a gold catalyst. alpha-Naphthol derivatives were obtained as products of the cycloisomerization. The close relationship of the products to the corresponding cyclizations implicated a related mechanistic scenary at first, but further studies favour a mechanistic pathway that is completely different.

  • 出版日期2015-10-15