摘要

Phosphoramidites, as a class of privileged chiral ligands, are suitable for different types of reactions, such as catalytic asymmetric hydrogenation, catalytic asymmetric allylic substitution, catalytic asymmetric Diels-Alder reaction and so on. Catalytic asymmetric hydrogenation reactions are some of the most important reactions in industry. In this review recent advances and applications of phosphoramidite ligands in Ir-catalyzed asymmetric hydrogenation of enamides and their derivatives, unfunctionalized enamines, imines and heteroaromatic compounds are discussed.