Update on ocular cicatricial pemphigoid and emerging treatments

作者：Queisi Munther M; Zein Mike; Lamba Neerav; Meese Halea; Foster Charles Stephen^*

来源：Survey of Ophthalmology, 2016, 61(3): 314-317.

DOI：10.1016/j.survophthal.2015.12.007

• mucus membrane pemphigoid
• ocular cicatricial pemphigoid
• chemotherapy
• alkylating agents
• biologic agents
• immunomodulatory therapy

Mucous membrane pemphigoid is a systemic disorder that primarily affects mucous membranes. When localized to the conjunctiva, it is known as ocular cicatricial pemphigoid, a potentially blinding disease. Ocular cicatricial pemphigoid is an indication for systemic immunosuppressive treatment to achieve adequate remission. Immunosuppressive agents are selected with a "stepladder" approach, commencing with medications having the fewest side effects. We provide an update of the literature on immunomodulatory agents since 2011 as additional treatment modalities have been explored in the last 4 years.

• 出版日期2016-6