An environmentally friendly Mukaiyama aldol reaction catalyzed by a strong Bronsted acid in solvent-free conditions

作者:Barbero Margherita*; Bazzi Stefano; Cadamuro Silvano; Dughera Stefano; Magistris Claudio; Smarra Alessandra; Venturello Paolo
来源:Organic and Biomolecular Chemistry, 2011, 9(7): 2192-2197.
DOI:10.1039/c0ob00837k

摘要

o-Benzenedisulfonimide, a new strong bench-stable Bronsted acid, has been shown to efficiently catalyze the Mukaiyama aldol reaction of aldehydes or dimethyl acetals with silyl enol ethers under mild solvent-free reaction conditions.

  • 出版日期2011