A straightforward access to pyrrolidine-based ligands for asymmetric synthesis

作者:Delaye Pierre Olivier; Ahari M'hamed; Vasse Jean Luc*; Szymoniak Jan
来源:Tetrahedron: Asymmetry , 2010, 21(20): 2505-2511.
DOI:10.1016/j.tetasy.2010.09.015

摘要

A straightforward and flexible method for the preparation of ligands based on the pyrrolidine scaffold is presented The synthetic strategy involves a diastereoselective allylation of phenylglycinol-derived imines followed by a cyclization pr

  • 出版日期2010-10-28