Allylation of Functionalized Aldehydes by Potassium Allyltrifluoroborate Catalyzed by 18-Crown-6 in Aqueous Media

作者:Barbosa Fernanda C G; Freitas Juliano C R; Melo Caio F; Menezes Paulo H; Oliveira Roberta A*
来源:Molecules, 2012, 17(12): 14099-14110.
DOI:10.3390/molecules171214099

摘要

An efficient method for the allylation of aldehydes containing a broad range of functional groups using potassium allyltrifluoroborate is described. The reaction utilizes a catalytic amount of 18-C-6 in biphasic media under open atmosphere and room temperature to provide the corresponding homoallylic alcohols in high yields and without the necessity of any subsequent purification.

  • 出版日期2012-12