A highly selective turn-on fluorescent and naked-eye colorimetric sensor for cyanide detection in food samples and its application in imaging of living cells

作者：Niu, Qingfen^*; Lan, Linxin; Li, Tianduo; Guo, Zongrang; Jiang, Tao; Zhao, Zhiyi; Feng, Zhenshuai; Xi, Jinying

来源：Sensors and Actuators B: Chemical , 2018, 276: 13-22.

DOI：10.1016/j.snb.2018.08.066

• Colorimetric
• Fluorescent sensor
• Cyanide
• Food samples
• Bioimaging

A novel highly selective oligothiophene-benzothiazole based sensor 3TBN has been developed for "naked-eye" colorimetric and fluorescent "turn-on" detection of cyanide in aqueous DMSO media. The sensor 3TBN exhibited distinct visual color and spectral changes in response to cyanide anion (CN-) over other tested anions. A good linear relationship was clearly observed between the fluorescence enhancement of the sensor 3TBN and the concentration of CN- in the wide range of 0-40 mu M with a low detection limit of 0.46 mu M. The sensing mechanism based on the nucleophilic addition reaction of the sensor with CN-on the cyanovinyl electrophilic C=C group has been well confirmed. Economically viable paper-based colorimetric test strips of 3TBN were fabricated to effectively detect the CN- ions in water. More importantly, as a cost-effective and selective fluorescent sensor, the sensor 3TBN has been successfully employed for detection of CN- in food samples and fluorescence bioimaging in living HeLa cells.

• 出版日期2018-12-10
• 单位山东省科学院