A rapid synthesis of quinoxalines starting from ketones

作者：Padmavathy K; Nagendrappa Gopalpur^*; Geetha K V

来源：Tetrahedron Letters, 2011, 52(4): 544-547.

DOI：10.1016/j.tetlet.2010.11.116

• 1,2-Diaminobenzene
• Diketomonoxime
• alpha-Hydroxylimino ketone
• Microwave
• Quinoxaline

A fast and general synthesis of quinoxalines, performed in two stages or as a one-pot reaction, starting from ketones via their alpha-hydroxylimino ketone derivatives, and condensation of the latter with 1,2-diaminobenzene under microwave irradiation, is described.

• 出版日期2011-1-26