A novel FRET-based ratiometric fluorescent probe for highly sensitive detection of hydrogen sulfide

作者:Huang, Kunzhu; Yu, Lun; Xu, Pengfei; Zhang, Xintong; Zeng, Wenbin*
来源:RSC Advances, 2015, 5(23): 17797-17801.
DOI:10.1039/c4ra16578k

摘要

A novel FRET-based ratiometric fluorescent probe H2S-CR for the quantitative detection of H2S was designed and synthesized. It exhibits a response time of 20 min, a considerable fluorescence signal enhancement (15 fold), and an extremely low detection limit (19 nM). It can be successfully applied to imaging H2S in living cells.