Systemic Amyloidosis Model on Young Mice

作者:Kozlov V A*; Sapozhnikov S P; Karyshev P B; Sheptukhina A I; Nikolaeva O V
来源:Bulletin of Experimental Biology and Medicine, 2017, 162(4): 520-523.
DOI:10.1007/s10517-017-3652-y

摘要

Subcutaneous daily injection (with neglect of aseptics) of 0.5 ml solution of soybean cream substitute (10% volume in distilled water) during 30 days caused systemic amyloidosis in 30-day-old mice. All the known methods for induction of systemic amyloidosis are based on the use of old animals, as senile tissue bradytrophy allows effective simulation of amyloidosis.

  • 出版日期2017-2