Degradability of porous composite scaffolds based on β-tricalcium phosphate-bioglass-poly lactic acid

作者：Zhao, Naru^*; Wang, Yingjun; Ye, Jiandong; Chen, Xiaofeng; Ning, Chengyun

来源：Journal of the Chinese Ceramic Society, 2007, 35(6): 679-682.

• Beta tricalcium phosphate
• Bioglass (BG)
• Degradability
• Induced coupled plasma spectroscopy
• Poly lactic acid (PLA)
• Simulated body fluid (SBF)
• Tissue engineering scaffold

Bioactive composites based on β-tricalcium phosphate (β-TCP), bioglass (BG) and poly lactic acid (PLA) were prepared. The microstructure, degradability and reaction products of the scaffold soaked in a simulated body fluid (SBF) for different days were characterized through a scanning electron microscope, X-ray diffraction, Fourier transform infrared spectroscopy, and induced coupled plasma spectroscopy. The porosity and specific areas were characterized by the Archimedes' method and nitrogen gas adsorption. The results show that at the same porosity, the degradability of the scaffold samples decrease as follows: β-TCP/BG/PLA> β-TCP/BG>β-TCP. The materials have highly bioactive responses to the SBFand promptly induce a bone-like hydroxyapatite layer on the surface of the scaffolds when immersed in the SBF.

• 出版日期2007-6
• 单位华南理工大学