New phosphine-imine and phosphine-amine ligands derived from D-gluco-, D-galacto- and D-allosamine in Pd-catalysed asymmetric allylic alkylation

作者：Szulc Izabela; Kolodziuk Robert; Zawisza Anna^*

来源：Tetrahedron, 2018, 74(13): 1476-1485.

DOI：10.1016/j.tet.2018.02.009

• D-glucosamine
• D-galactosamine
• D-allosamine
• Iminophosphine
• Aminophosphine
• Homogeneous catalysis
• Asymmetric alkylation
• Palladium

New phosphine-imine and phosphine-amine chiral ligands which were easily prepared from D-gluco-, D-galacto-and D-allosamine furnished a high level of enantiomeric excess (up to 99%) in the Pd(0)-catalysed asymmetric allylic alkylation of racemic 1,3-diphenyl-2-propenyl acetate with malonates.

• 出版日期2018-3-29