Postnatal Inflammation in the Pathogenesis of Bronchopulmonary Dysplasia

作者：Bhandari Vineet^*

来源：Birth Defects Research Part A: Clinical and Molecular Teratology , 2014, 100(3): 189-201.

DOI：10.1002/bdra.23220

• invasive ventilation
• infection
• hyperoxia
• lung
• newborn

Exposure to hyperoxia, invasive mechanical ventilation, and systemic/local sepsis are important antecedents of postnatal inflammation in the pathogenesis of bronchopulmonary dysplasia (BPD). This review will summarize information obtained from animal (baboon, lamb/sheep, rat and mouse) models that pertain to the specific inflammatory agents and signaling molecules that predispose a premature infant to BPD. Birth Defects Research (Part A) 100:189-201, 2014.

• 出版日期2014-3