A Unifying Nitrososynthase Involved in Nitrosugar Biosynthesis

作者:Hu Yunfeng; Al Mestarihi Ahmad; Grimes Catherine L; Kahne Daniel; Bachmann Brian O*
来源:Journal of the American Chemical Society, 2008, 130(47): 15756-+.
DOI:10.1021/ja8051415

摘要

Herein we describe the cloning, functional expression and initial characterization of ORF36 from Micromonospora carbonacae var. africana and rubN8 from Streptomyces achromogenes var. rubradiris. The purified enzymes play the same role, the double-oxidation of TDP-evernosamine to TDP-evernitrosose in the everninomycin and rubradirin pathways, respectively.

  • 出版日期2008-11-26