摘要
An efficient and convenient multicomponent reaction for the preparation of 4-aryl-2-oxo-2,5-dihydro-1H-indeno[1,2-b]pyridine-3-carbonitrile and 4-aryl-2-oxo-1,2,5,6-tetrahydrobenzo[h]quinoline-3-carbonitrile derivatives by the 2,3-dihydroinden-1-one or 3,4-dihydronaphthalen-1(2H)-one, aromatic aldehydes, and malononitrile in the presence of sodium hydroxide under solvent-free condition is reported. The short reaction time coupled with the simplicity of the reaction procedure makes this method one of the most efficient methods for the synthesis of these classes of compounds.
- 出版日期2009-5
- 单位江苏师范大学