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摘要
A novel approach to pattern silanized-biomolecules directly onto glass (SiO(x)) substrates via Dip-Pen nanolitho-graphy (DPN) and microcontact printing (mu CP) is presented. Subsequent hybridization reactions of DPN patterned silanized-DNA with its complementary strands provide "proof-of-concept" that the patterned oligonucleotides maintain their biological activities. The fabrication strategy does not require premodification of substrates and offers a cheap and robust way to immobilize molecules on electronically important semiconductor surfaces.
- 出版日期2010-12-7
