The feasibility of growing cells of Saccharomyces cerevisiae for citronellol production in a continuous-closed-gas-loop bioreactor (CCGLB)

作者：Arifin Aimi Aishah; Don Mashitah Mat; Uzir Mohamad Hekarl^*

来源：Bioresource Technology, 2011, 102(19): 9318-9320.

DOI：10.1016/j.biortech.2011.07.053

• Biotransformation
• Monoterpene
• Saccharomyces cerevisiae
• Continuous-closed-gas-loop bioreactor (CCGLB)
• Reduction

The present work aims to address the gas-phase biotransformation of geraniol into citronellol using growing cells of Saccharomyces cerevisiae (baker's yeast) in a continuous-closed-gas-loop bioreactor (CCGLB). This study revealed that the gaseous geraniol had a severe effect on the production of biomass during the growing cell biotransformation resulting in the decrease in the specific growth rate from 0.07 to 0.05 h(-1). The rate of reaction of the growing cell biotransformation was strongly affected by agitation and substrate flow rates. The highest citronellol concentration of 1.18 g/L and initial rate of reaction of 7.06 x 10(-4) g/min g(cell) were obtained at 500 rpm and 8 L/min, respectively.

• 出版日期2011-10