Direct chemiluminescence detection of circulating microRNAs in serum samples using a single-strand specific nuclease-distinguishing nucleic acid hybrid system

作者：Ling, Kai^*; Jiang, Hongyan; Huang, Xue; Li, Yang; Lin, Juanjuan; Li, Fu-Rong^*

来源：Chemical communications, 2018, 54(15): 1909-1912.

DOI：10.1039/c7cc09087k

• CANCER
• MECHANISM
• BIOMARKER
• ARRAY

We developed a microplate-based enhanced chemiluminescence system for the direct detection of circulating miRNAs. The system exhibited a high target sensitivity and specificity, with a detection limit of 3.02 fM.

• 出版日期2018-2-21
• 单位汕头大学; 暨南大学