Acute-phase protein behavior in dairy cattle herd naturally infected with Trypanosoma vivax

作者：Sampaio Paulo Henrique^*; Fidelis Junior Otayio Luiz; Marques Luiz Carlos; Machado Rosangela Zacarias; Barnabe Patricia de Athayde; Andre Marcos Rogerio; Balbuena Tiago Santana; Cadioli Fabiano Antonio

来源：Veterinary Parasitology, 2015, 211(3-4): 141-145.

DOI：10.1016/j.vetpar.2015.05.014

• Trypanosomiasis
• Bovine
• Tandem mass spectrometry
• Host-parasite relationship

Trypanosoma vivax is a hemoprotozoon that causes disease in cattle and is difficult to diagnose. The host-parasite relationship in cattle that are infected by T. vivax has only been poorly studied. In the present study, a total of 429 serum proteinograms were produced from naturally infected animals (NIF) and were compared with 50 samples from control animals (C). The total protein, IgA band, complement C3 beta chain band, albumin band, antitrypsin band, IgG band, haptoglobin band, complement Cc a chain band and protein HP-20 band presented higher levels in the serum proteinograms of the NIF group. Inter-alphatrypsin inhibitor heavy chain H4, alpha 2-macroglobulin, complement C6, ceruloplasmin, transferrin band and apolipoprotein Al band presented lower levels in this group. There was no significant difference (p < 0.05) in acid glycoprotein serum concentration between the NIF and C groups. Acute phase proteins may be useful for understanding the host-parasite relationship, since the antitrypsin band was only present in the NIF group. This can be used as an indicator for infection in cattle that are naturally infected by T. vivax.

• 出版日期2015-7-30